James Otis Sargent Huntington was one of the founders of the Order of the Holy Cross.

He was born in Boston in 1854. After graduating from Harvard, he studied theology at St. Andrew's Divinity School in Syracuse, and was ordained deacon and priest by his father, the first Bishop of Central New York. While attending a retreat in St. Clement's Church, Philadelphia, he received a call to the monastic life. He considered joining the Society of St. John the Evangelist, an English order that had established a province in the US, but he decided to found an indigenous American community.

Huntington and two other priests began their common life at Holy Cross Mission on New York's Lower East Side, ministering with the Sisters of St. John Baptist among poor immigrants. In 1902 the Order moved to West Park, New York, where it established the monastery which is its mother house.

Huntington died in 1935. In the early years of St. Andrew's, there was a close association with the Order of the Holy Cross, and several times priests from the order served as supply clergy for this parish.

His Feast Day is November 25.